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The recommended dosage regimen may involve an initial loading dose followed by maintenance doses at regular intervals

After this initial period, you can choose to receive injections as and when you feel like you need them, based on your individual needs and preferences

High-dose B12 therapy is usually safe

However, CMS continues to defer to SAMHSA guidance on the use of audio-only telecommunications for initiation of treatment with methadone pursuant to 8.12(f)(2)(v)(A), which allows a specific exception to allow for the use of audio-only devices when the patient is in the presence of a licensed practitioner who is registered to prescribe (including dispense) controlled medications, and when audio-visual technologies are not available or their use is not feasible for a patient (89 FR 7539)