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Vitamin B12 is essential for red blood cell formation, DNA synthesis, and maintaining the myelin sheath that insulates nerve fibers

2 During pregnancy, calcium availability in the body increases through increased absorption of calcium from foods, increased mobilization from bones, and decreased calcium loss through the kidneys

(2017) 9(401):eaah6733

eADO can be catabolized to inosine by adenosine deaminase (ADA) or transported into cells by the nucleoside transporters ENT1/2 or CNT1/2 (106)

Metabolites or even short RNAs directly act on receptors and ion channels (GABA receptors, TLRs, TRP channels, acid-sensitive ion channels) expressed by nociceptive primary afferents, and induce nociceptor activation and sensitization (Lutz et al., 2014