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recently demonstrated that overactivation of NF-B prevents BMAL1 binding to the promoter region of PER2 and, consequently, its transcription in human omental fat 73

Saeki I, Yamamoto N, Yamasaki T, Takami T, Maeda M, Fujisawa K, et al

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity