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While still highly significant versus baseline, the high-dose group actually produced fewer new hairs than the low-dose group consistent with the biphasic dose-response seen in the 2007 Pyo laboratory study where higher copper peptide concentrations inhibited rather than stimulated growth

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Expressions of cleaved Caspase-1, GSDMD-NT, IL-18, and the secretion of IL-1 are also increased in the kidneys of db/db mice (127)