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Lee JY, Yoo JM, Cho BK, Kim HO

It is usually performed when the cancer is recurrent type and when tissue conservation is needed

Network pharmacology analysis has shown that the phosphoinositide 3 kinase/protein kinase B (PI3K/AKT) pathway and proteins, such as epidermal growth factor receptor, recombinant MAPK kinase 1 (MAP2K1), and MMP-2, are key targets for curculigoside therapy (285)

Croley anchors candidacy to medical indications and overall health status: stable vital signs, adequate renal and liver function, and a good-faith medical exam by a provider authorized to prescribe these treatments

More notably, they highlight that competition between lactylation and acetylation may arise directly from shared catalytic machinery: When multiple acyl-CoA species coexist in the nucleus, they may compete for occupancy of the same acyl-CoA channel within p300, thereby influencing the balance between distinct PTMs