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It comes from understanding how they work together

This drop in pH levels can impair the ability of the antioxidant defense system to neutralize free radicals, leading to an accumulation of oxidative stress

Signal 20, 174

Oxidized lipids, produced by the autooxidation of polyunsaturated fatty acids [arachidonic acid (AA), alpha-linolenic acid, DHA, Eicosapentaenoic acid (EPA), etc.] or by enzyme action, have been linked to cardiovascular diseases [60]