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The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

Failures in drug development can often be attributed to gaps in our understanding of the biological underpinnings of human diseases, an overreliance on nonhuman models, and deficiencies such as low specificity, suboptimal pharmacological properties, or severe adverse reactions to drugs

Large alpha-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

10.1007/s11356-019-07511-x 160 VizsnyiczaiG.FrangipaneG.BianchiS.SaglimbeniF.DellArcipreteD.Di LeonardoR

Having previously conducted a series of investigations of the oxidative damage theory that did not support it [34-38], we were curious about the life-extending effect of GSH, which is consistent with this theory