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These include the ACNs, catechins (flavan-3-ols), chalcones, flavones, flavanones, isoflavones, and flavonols [98]

From a mechanistic perspective, it was shown that spermidine was required for the posttranslational activation of the eukaryotic translation initiation factor eIF5A (i.e., hypusination), essential for cell division 42,43