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Elevated levels of total immunoglobulin E (IgE) and pro-inflammatory cytokines such as interleukin (IL)-4, IL-13, IL-22 and IL-31 can increase ROS production and vice versa, further contributing to the pathophysiology of AD (20, 24)

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In the main root, the greatest elevation of the five enzyme activities was observed in the 0.5 mmol/L-treated group, HMGCR and FPS peaking on day 2, and SS, SE, and DS on day 3

Antibodies against p16 ink4a (polyclonal, ab108349), B2M (monoclonal, ab75853), high mobility group protein 1 (HMGB-1) (ab228624), matrix metalloprotein 13 (MMP-13) (ab39012), and type II collagen (Col-2) (ab34712) were from Abcam (UK)

Modification of cellular autophagy protein LC3 by poliovirus