Berberine Integrative Therapeutics Metabolic Support* Product Details Brand: Integrative Therapeutics Category: Vitamins & Supplements Product Code: berberine-INT Servings per Container: 60 METABOLIC SUPPORT* Berberine offers metabolic support for glucose and lipid metabolism.* It also supports healthy blood sugar and insulin levels already within a normal range.* Also supports healthy gastrointestinal function.* HOW IT WORKS Clinical studies demonstrate that berberine supports healthy lipid metabolism and cholesterol homeostasis.*1-6 Berberine can activate an important metabolic enzyme known as adenosine monophosphate-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis.* Mechanistic research in vitro and in vivo suggests that berberine can decrease cholesterol and triglyceride synthesis by activating AMPK.7-9 In addition to supporting lipid metabolism, berberine supports healthy glucose metabolism and blood sugar management already within a normal range.*2-5 Mechanistic research in vitro suggests that berberine can support healthy glucose regulation through promoting glucose uptake in cells via GLUT4 translocation.7 REFERENCES Kong W et al
Research has shown that centelloside selectively regulates the Nrf2 pathway, increasing the expression of Nrf2, GPX4, and SLC7A11 in a kidney injury model, inhibiting oxidative stress and ferroptosis, alleviating LPS-induced vacuolation and glomerular mesangial expansion in kidney tissues, to reduce AKI (188)
In perturb-Seq, an initial perturbation, typically in the form of a CRIPSR-based modification, is performed, and this is followed by sequencing via single cell RNA seq (scRNA-seq) [39]
GPx1, Glutathione peroxidase 1
Chen W, Ohara N, Wang J, et al
