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10.1016/j.bcp.2019.02.008 96 NeelakantanH.VanceV.WetzelM

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Liver Health and Anti-Steatosis Activity: Reverses diet-induced hepatic steatosis by normalizing liver fat content to lean control levels, reduces liver adiposity by over 45%, improves hepatic metabolic profiles, and shifts lipid metabolism away from de novo synthesis toward enhanced fatty acid oxidation 2

NNMT (nicotinamide N-methyltransferase) is an enzyme that methylates nicotinamide, diverting it from NAD+ synthesis