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3b): (i) Synthesis of the N-acetyl--D-glucosamine-caged NIR-I chemiluminescent substrate 8 , (ii) synthesis of the trifluoromethanesulfonate-caged NIR-II chemiluminescent substrate 10 , and (iii) conjugation of NIRF-I and NIR-II chemiluminescent substrates ( 8 & 10 ) followed by oxidation to afford CAR

Figure 5: Acetaldehyde, a byproduct of alcohol, disrupts the balance between SAM and SAH

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