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ISBN 978-0-13-149330-8

doi: 10.3389/fcell.2025.1671152 Received 22 July 2025 Revised 08 October 2025 Accepted 20 October 2025 Published 01 December 2025 Volume 13 - 2025 Edited by Nimanthi Jayathilaka, University of Kelaniya, Sri Lanka Reviewed by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Arturo Raya-Sandino, University of Michigan, United States Updates Copyright 2025 Ferris, Subitoni Antonio and Al-Sadi

Remove the needle from the vial carefully

However, one of the waste products of cellular energy generation is free radicals, which are highly reactive molecules that can damage cells, membranes, lipids, proteins and DNA

e) New Checkpoint Inhibitors: Beyond PD-1 and CTLA-4 inhibitors, researchers are developing novel checkpoint inhibitors targeting other immune checkpoints