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In both MASLD and ALD, the presence of abnormal lipids can result in lipid toxicity, leading to subsequent inflammation, oxidative stress, ERS, and other related pathologies

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The recommended dosage of Pemetrexed Injection when administered with cisplatin for initial treatment of locally advanced or metastatic non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes administered prior to cisplatin on Day 1 of each 21-day cycle for up to six cycles in the absence of disease progression or unacceptable toxicity

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