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It is particularly helpful for those exposed to environmental pollutants, high stress, or oxidative strain

Epigenet 14, 72

The key regulatory point of the PPP is the enzyme glucose-6-phosphate dehydrogenase (G6PD), which catalyzes the first and rate-limiting step of the oxidative phase

A., Schattling, B

This step is generally considered the rate-limiting step, with the availability of cysteine and the expression level of GCLC jointly determining the rate of -Glu-Cys production