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Figure 3 Elevated GPX4 and Ferrous Iron Are Potential Therapeutic Targets of CRC Persister Cells and Tumors The key event in ferroptosis is cell membrane damage associated with peroxidation of lipids ( GPX4 expression

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D P Jones, R J Coates, E W Flagg, J W Eley, G Block, R S Greenberg, E W Gunter, B Jackson - Glutathione in foods listed in the National Cancer Institute's Health Habits and History Food Frequency Questionnaire - Nutr Cancer - 1992

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To assess whether MitoQ treatment can similarly overcome the differentiation block observed with DPI (16), MNA IMR-5/75 cells were treated every two days with either 50 nM or 100 nM MitoQ and monitored by microscopy ( Figure 1G )