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Previous studies reported about 3-fold elevation in the risk for ARDS in otherwise healthy alcohol abusers

During sleep, this pressure is ameliorated by removing scavenging free radicals with antioxidant enzymes which can be regulated with sleepwake modulators like melatonin

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These data indicate that genes associated with metabolic ROS generation tend to be upregulated in MZB compared to FoB, suggesting that differences in the control of ROS signaling might contribute to the classical distinctions between these two mature B cell subsets