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In geographical areas where winter temperatures go below the freezing point of water, using pure water as the coolant could allow the water to freeze

Morphine is typically used to treat infants with neonatal abstinence syndrome

People assigned female at birth (AFAB) are more likely to develop it than those designated male at birth (AMAB)

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The cooling causes a reduction in blood flow to the scalp, so less of the chemotherapeutic drugs reach the hair follicles (van den Hurk 2013)