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The concentration of serotonin can be modulated by the gut microbiome in multiple ways [230], most notably shown by altered concentration of serotonin and its metabolites in the hippocampus of germ-free animals [231]

doi: 10.1016/j.freeradbiomed.2022.08.021 106 ZarkoviM

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Gastrointestinal dysmotility and/or diarrhoea occurs after the acute phase of CDI, but persistent gastrointestinal dysfunction post-infection supports contributions of neuroplasticity in the enteric nervous system (ENS), which has a key role in regulating intestinal motility and secretion, in the natural course of CDI

Vitamin B12 is a vital nutrient our body uses to keep our red blood cells healthy