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vegans require fortified foods or supplements of 10 mcg daily or 2,000 mcg weekly Long-term metformin use and proton pump inhibitors can impair B12 absorption and may require monitoring Table of Contents Recommended Daily B12 Intake in the UK Vitamin B12 (cobalamin) is an essential water-soluble vitamin that plays a critical role in red blood cell formation, neurological function, and DNA synthesis

There is no consensus on the interpretive criteria used to define inadequate B12 status with these B12 biomarkers

This may represent a normal part of follicle cycling acceleration rather than a true adverse effect

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Yuejun Zheng, et al