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Banumathy, G., Singh, V

Nat Rev Immunol (2009) 9(5):31323

Postmortem analyses have confirmed astrocyte activation in the substantia nigra of PD patients, accompanied by elevated pro-inflammatory cytokines [tumor necrosis factor- (TNF-), IL-1, transforming growth factor-, and IL-6], ROS, NO, pro-apoptotic proteins, and T-cell infiltration