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H 2 S metabolism, though not extensively studied in early life, likely plays crucial roles in cardiovascular transition, 52,53 homeostasis, 54 vasoactivity in synergy with NO, inflammation, and oxidative stress regulation

A synthetic compound called carbonyl cyanide-m-chlorophenyl hydrazone (CCCP) was found to act as a decoupler that disrupts the proton motive force of the pump, resulting in an antibiotic-potentiating effect with tetracycline against Helicobacter pylori and Klebsiella , alleviating gastrointestinal tract-associated diseases 82,83

Modifications to major biomolecules can occur through the direct and indirect actions of reactive intermediates and/or reactive oxygen species (ROS), which in turn can arise from the metabolism of both exogenous and endogenous chemicals during inflammation, radiation and the metabolism of hormones, drugs and environmental toxins Citation[15]

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Upconversion nanoprobes: recent advances in sensing applications