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Together, these mechanisms underscore the intricate interplay of oxidative stress, lipid metabolism, and iron dysregulation in driving ferroptosis ( Figure 1 )

Claudin-5, a key transmembrane protein, forms the backbone of these tight junctions, directly contributing to the barrier's resistance to the passage of molecules

These vitamins include vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B5 (pantothenic acid), vitamin B7 (biotin), and vitamin B12 (cobalamin) ( Its important to note that while these vitamins have no observable toxicity, some of them may interact with medications and interfere with blood testing results

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