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Arimoto T, Choi DY, Lu X, Liu M, Nguyen XV XV, Zheng N, et al

The innate response can provide an instructive role for cells of the adaptive immune system through the production of pro-inflammatory mediators, including chemokines, and cytokines, the induction of co-stimulatory activity by phagocytic cells, and antigen uptake and presentation (Romani, 2011)