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Rating: 4.4509 (25 reviews)

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Description

Consequently, mutations in TP53 lead to a loss of this repression, resulting in sustained SLC7A11 activity and greater cellular resistance to ferroptosis (Leu et al., 2019)

Food Chem 2007;102:76470

Next, whether silencing of these genes specifically attenuated erastin-induced ferroptosis, or more broadly modulated a variety of lethal effects was tested