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Mouse model has been verified to be powerful for hematologic tumor research in several studies [41]

However, we found smaller changes in gene content related to the regulation of gene expression and signaling that may account for the ability to grow at high temperature, species specific morphological transitions, and therefore their differences in virulence, since rapid thermo-tolerance and morphological adaptation is essential for pathogenesis 29,30,43

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In a properly managed clinic, infection rates are very low