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Methods: We retrospectively analyzed CTAs from 343 patients from the MR CLEAN trial, divided into 274 training and 69 test patients

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One user connected their symptoms to their new diet: "Its likely from all the weight loss and from changing my diet and eating far less overall." - thcitizgoalz Rapid weight loss itself can create deficiencies

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The following FBXO3 crRNA guides were ordered from IDT and used: sgFBXO3-3: GGAGGATTCCAGCAGAGACA sgFBXO3-4: TATCAAGTCATGATCCGCTG sgFBXO3-5: TGTTCATACCGAATTCACAA sgFBXO3-6: GACGTCGATACAGCTGCCGG Endpoint HiBiT protein degradation HiBiT reporter cells, generated as described above, were seeded into 384-well plates at 20,000 cells per well and treated with the indicated compounds and equivalent concentrations of DMSO for the time indicated in the experiment, usually 3, 24 or 72 h