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These nanoparticles exert antitumor activity through the combined effects of erastin-induced ferroptosis and the Fenton reaction, both of which contribute to increased ferroptosis [159]

Conversely, FDX1 causes the destabilization of Fe-S cluster proteins

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However, other forms of HH, known as non-HFE haemochromatosis, also share the trait of having low plasma hepatic phospholipid levels that are out of proportion to the bodys iron levels