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Free radicals target the melanocytes in the hair bulb and attack in particular the DNA of their mitochondria

formation of double-membrane enclosed vesicles) ( 2 O 2 , but not erastin, STS or rapamycin, was observed ( Using a variation of the modulatory profiling strategy (Wolpaw et al., 2011), the ability of twelve established small molecule cell death inhibitors to prevent ferroptosis in HT-1080, BJeLR and KRAS-mutant Calu-1 non-small cell lung cancer cells was tested

Altered expression of -glutamyl transpeptidase in human tumors

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha

GSH serves as a primary intracellular antioxidant, and cysteine availability plays a critical role in maintaining GSH levels, as supply of cysteine is the rate-limiting step in GSH synthesis [16, 26]