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On the one hand, its activation can promote cancer progression, invasion, metastasis, and resistance to chemotherapeutic agents [68]

Sortase A-mediated cyclization of novel polycyclic RGD peptides for 3 integrin targeting

[DOI] [PMC free article] [PubMed] [Google Scholar] 389.Scarangella A, Soldan V and Mitov M, Nat

doi: 10.3389/fphar.2025.1661443 Received 07 July 2025 Revised 07 December 2025 Accepted 16 December 2025 Published 02 March 2026 Volume 16 - 2025 Edited by Michael Heinrich, University College London, United Kingdom Reviewed by Phiwayinkosi V