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Polyphenols further reinforce these antioxidant defenses by scavenging free radicals and activating nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of oxidative stress response genes [252]

Further results from in vitro desuccinylation assays also demonstrated that HA-SIRT2 protein purified from HA-SIRT2 overexpressing HEK293T cells could efficiently desuccinylate GCLC in the presence of NAD + (Fig

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The G6PD-deficient cells in females, however, are as vulnerable to hemolysis as are enzyme-deficient red blood cells in males