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Liao, Y., Smyth, G

Metabolomics in multiple sclerosis

Besides, protein undergoes carbonylation, another form of protein oxidative modification in which ROS groups bind to specific amino acids, affecting protein stability and activity (46)

2.2 Neuroprotection-focused medications While IOP reduction remains the primary clinically validated method for controlling glaucoma and slowing disease progression, it is increasingly recognized that developing neuroprotective strategies is essential

In the OC model, Anisomycin not only significantly promoted the accumulation of Fe + , but also induced oxidative damage to cell membrane lipids, ultimately triggering ferroptosis signals (179)