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Cysteine, one of the three amino acids in glutathione, contains sulfur and often becomes the limiting factor in production

NAC might actually act as a pro-oxidant and might lower GSH and increase the amount of oxidized GSH

In primary rat hippocampal neurons, changes to endogenous APP cleavage and the abundance of CTFs were once again observed upon RABGAP1 KD (Appendix Fig

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The identification of alternative targets of HIF hydroxylases is important in order to fully elucidate the pharmacology of hydroxylase inhibitors (PHI)