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Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain

Vegetarians and vegans are particularly at risk of this deficiency, as they do not consume animal-derived foods that are rich in Vitamin B12

No pharmacokinetic data exists for severe renal impairment below a creatinine clearance of 20 mL/min, and clinical caution is warranted in this subgroup

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Varying amounts of monobromobimane stock solution (0-300 l) were added to respective cuvettes already containing 5 l of the enzyme solution (protein concentration of 810 g ml -1 ), glutathione (100 l of stock solution) and phosphate buffer (3.0 ml)