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1 Introduction OSAHS is primarily characterized by the recurrent partial or complete obstruction of the upper airway during sleep, leading to chronic intermittent hypoxemia and associated pathophysiological consequences, including disrupted sleep architecture, prolonged sympathetic activation, and carbon dioxide retention (1)

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[18] His next film project, the 1993 self-aware action comedy spoof Last Action Hero , was released opposite Jurassic Park , and did not do well at the box office

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Topical: 0.1-0.3% serum/cream twice daily for maintenance