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Mangiferin has been demonstrated to possess several beneficial properties, including antioxidant, antimicrobial, antidiabetic, antiallergic, neuroprotective, cardiovascular protective, anticancer, hypocholesterolemic and immunomodulatory effects

Mitochondrial respiratory chain inhibitors induce apoptosis

One potential mechanism of action under discussion is the reduction of pro-inflammatory lipid metabolites (prostaglandin E2) and NF-B induced cytokines as well as a reduced activity of growth receptors due to altered membrane lipids

doi:10.1021/acs.bioconjchem.0c00209 Wu H, Chen F, Gu D, You C, Sun B

Ann Trop Med Parasitol