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Thigmotaxis is an often described behavior pattern in transgenic mice and refers to an animal's tendency to remain close to the walls of its environment 46

Phase (approx.) Cagrilintide dose Frequency Weeks 14 0.25 mg Once weekly Weeks 58 0.5 mg Once weekly Weeks 912 1.0 mg Once weekly Weeks 1316 1.7 mg Once weekly Week 17 onward 2.4 mg (max studied) Once weekly This step-wise schedule mirrors the titration used in cagrilintide and CagriSema studies ( Lau et al., Lancet 2021

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Morning application ensures consistent daily use for those who sometimes skip evening skincare

This protects the peptide structure and ensures even dissolution