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Although these patients have extremely low NSP activity, they do not exhibit obvious immunodeficiency symptoms, providing important theoretical support for the safety of DPP1 inhibition therapeutic strategies ( Research indicates that neutrophil function in PLS patients shows specific abnormalities, including: reduced chemotaxis, affecting neutrophil directed migration

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It should be used as part of a comprehensive health and wellness strategy that includes a balanced diet, regular exercise, and good sleep hygiene