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In rats, GCLC has a Km for glutamate that is about 10-fold higher, which is higher than the cellular glutamate concentration in most tissues

Existing drugs called biologics can be highly effective but they are costly and rationed in the UK

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and 3 ) the concomitant presence of confounding events at the peripheral level associated with complications of the pathology or comorbidities present

2.12 OCLN immunofluorescence After GDC treatment, monolayers were washed twice with PBS and fixed for 30 min at room temperature by adding 500 L 75% ethanol in PBS to the apical chamber