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Furthermore, Aldehyde dehydrogenase 1A3 (ALDH1A3) was observed to promote the tetramerization of PKM2, which facilitates lactate-induced lactylation of X-ray cross-complementing protein 1 (XRCC1) at the K247 site, directly leading to a diminished response of tumor cells to TMZ and radiation therapy

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GHK-Cu demonstrates superior effects for skin, surface wounds, and hair while also providing systemic gene expression benefits

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GHR upregulation and fibroblast activation: BPC-157 enhances growth hormone receptor expression and drives fibroblast proliferation through FAK-paxillin signaling, producing organized collagen deposition rather than scar tissue