Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether 2341796-77-6 (2HCl salt) Molecular Formula

2341796-77-6 (2HCl salt) Molecular Formula C29H45Cl2N5O4S Molecular Weight 630

Product Name: Lissamine rhodamine B PEG3 alkyne Synonyms: Sulforhodamine B PEG3 alkyne CAS Number: N/A Molecular Formula: C36H45N3O9S2 Molecular Weight: 727

Product Name Trametinib Synonyms CAS Number 871700-17-3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether 2341796-77-6 (2HCl salt) Molecular FormulaSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I