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NICE has published guidance on pharmacological interventions for weight management, including NICE guideline CG189 (Obesity: identification, assessment and management) and a technology appraisal supporting the use of semaglutide (Wegovy) for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside a specialist weight management service

The symptoms in patients are severe and often accompanied by functional impairments, especially in the obese population

LTI: long-term injury groups

The published literature investigates cagrilintide as a tool compound in amylin and calcitonin-receptor signalling and in metabolic-pathway model systems

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