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2.3 Endothelial-to-mesenchymal transition EndMT is a process in which ECs transform into mesenchymal stem cells under certain pathological situations, such as high oxidative stress, disturbed metabolism, hypoxia, and shear stress force (38)

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In other words, they can reduce the spontaneous firing of nerves, which may, in turn, reduce the tinnitus

The regulation of self-renewal is therefore a delicate balance that must be tightly controlled to prevent the over proliferation of stem cells