Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP texas red In a study using TMR-d12-SHTL

In a study using TMR-d12-SHTL

21 Purity (HPLC) >= 95% Solubility DMSO

by coordinating through its four nitrogens and four carboxylate oxygen atoms

Product Name Thalidomide-O-acetamido-C5-acid Synonyms Thalidomide-4'-O-acetamido-C5-acid CAS Number 2354352-06-8 Related CAS Molecular Formula C21H23N3O8 Molecular Weight 445

eLife 2020

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP texas red In a study using TMR-d12-SHTLSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine