FPFT-2216 Size:5mg DCAF1-based PROTACs with activity against

DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

Product Name 4-(methoxy-d3)aniline Synonyms 4-(²H3)methoxyaniline CAS Number 1820684-56-7 Related CAS Molecular Formula C7H9NO Molecular Weight 126

584 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate Synonyms 1-Boc-4-(3-aminopropyl)piperazine CAS Number 373608-48-1 Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

338 SMILES OC(=O)CCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

FPFT-2216 Size:5mg DCAF1-based PROTACs with activity againstFPFT 2216 is a molecular glue compound. It promotes degradeation of phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1a (CK1a). Product Name FPFT 2216 Synonyms CAS Number 2367619 87 0 Related CAS Molecular Formula C12H12N4O3S Molecular Weight 292. 31 SMILES COC1=CSC=C1C1=CN(N=N1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF Shipping Conditions