Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg Product Name Thalidomide-5'-O-PEG2-OH Synonyms CAS

Product Name Thalidomide-5'-O-PEG2-OH Synonyms CAS Number 2328212-84-4 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362

Product Name tert-butyl 3-[2-(piperazin-1-yl)ethoxy]propanoate Synonyms CAS Number n/a Related CAS Molecular Formula C13H26N2O3 Molecular Weight 258

46 SMILES OCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

692 Purity (HPLC) >= 95% Solubility DMSO

768 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg Product Name Thalidomide-5'-O-PEG2-OH Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX