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Luciferase reporter assays (LRA) showed that GSTA1*A is more highly expressed than GSTA1*B 21 , most likely due to selective binding of Sp1 transcription factor (TF) at positions -52 and -69 21

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Tocopherol (Vitamin E): A powerful antioxidant that protects against free radical damage

Collectively, these findings highlight lipid-related PTMs as critical DDR regulators and potential therapeutic targets in cancer

Upon activation, proapoptotic proteins form pore complexes on the mitochondrial membrane, resulting in the loss of the mitochondrial membrane potential and the release of apoptotic factors such as cytochrome C, thereby activating the caspase-9/3 cascade [46]