Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate Synonyms

Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate Synonyms CAS Number 1181972-47-3 Related CAS Molecular Formula C14H29N3O3 Molecular Weight 287

977 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C4-azide Synonyms Thalidomide-4'-O-acetamido-C4-azide CAS Number 2098488-36-7 Related CAS Molecular Formula C19H20N6O6 Molecular Weight 428

(R)-CR8 acts as a molecular glue degrader that depletes cyclin K

Product Name: 5-FAM azide Synonyms: 5-Carboxyfluorescein azide CAS Number: 510758-23-3 Molecular Formula: C24H18N4O6 Molecular Weight: 458

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The