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The widely used 3xTg mouse model, which contains three mutations associated with familial Alzheimers disease, can display anxiety-like behaviors through behavioral paradigms such as the OFT and EPM test as early as 2 months of age (Paciello et al., 2021)

Several phytochemical nanoformulations, such as paclitaxel (Abraxane ), irinotecan (Onivyde ), vinorelbine (NanoVNB ), vincristine (Marqibo ), and docetaxel (DoceAqualip ), are already FDA-approved for cancer therapy (Dhupal and Chowdhury, 2020), while multiple curcumin-, camptothecin-, ursolic acid-, mangiferin-, and quercetin-based platforms are undergoing clinical evaluation in liposomal, polymeric, micellar, and plant-derived nanocarriers (Devan et al., 2023

Chronic psychological stress raises cortisol and inflammatory cytokines, both of which consume glutathione

Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs