Fmoc-Val-Cit-PAB(m-PEG4) cleavable Distinct beta-arrestin coupling and intracellular

Distinct beta-arrestin coupling and intracellular trafficking of metabotropic glutamate receptor homo-and heterodimers

Product Name GSK1790627 Synonyms CAS Number 871701-87-0 Related CAS Molecular Formula C24H23FIN5O4 Molecular Weight 591

612 SMILES: OC(=O)C1=CC=C(C([O-])=O)C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

736 Purity (HPLC) >= 95% Solubility DMSO

NCCCCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB(m-PEG4) cleavable Distinct beta-arrestin coupling and intracellularSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned